CRC Living with Autism

Cooperative Research Centre (CRC) Living with Autism

The Federal Government in its press release1 dated 6 March 2014 allocated $31M in cash over eight years to the CRC. Further funding (~$70M in cash and in kind) will be forthcoming from the 49 participating organisations. The CRC has three programs:

  1. A better start through better diagnosis
  2. Enhancing learning and teaching
  3. Finding a place in society

Program 1 is focused on better diagnosis with a view to finding biomarkers which will enable diagnosis to be made much earlier than is presently possible through psychological assessment. In this respect the aims of this program are similar to those of BioAutism Ltd. To this end the CRC has set up The Australian Autism Biobank which will collect blood samples from patients aged 2-17 with a confirmed diagnosis of autism in WA, Vic, NSW, and Qld, and the DNA will be analysed for unusual genetic characteristics (SNPs and/or CNVs)2 which may be useful biomarkers for autism. Parental blood samples are also required. Further information is available at http://otarc.blogs.latrobe.edu.au/the-australian-autism-biobank-an-invitation-to-participate/?utm_source=Exact-Target&utm_medium=email&utm_campaign=Newsletter%20-%20March%202015%20Issue%2027

The CRC's Annual Report for 2014/15 shows details of cash funding and In-Kind Value for Program 1 provided by the various institutions (mainly universities) involved3.

Project

Short title

Years

Lead Investigator/

Institution

Project Funds ($k)

In-Kind Value ($k)

1.002RC

Creation of biobank

2013-16

Andrew Whitehouse (UWA)

152

751

1.003RC

Genetic screening (Phase 1)

2013-16

Charles Claudianos (UQ)4

537

1,845

 1.018RI

Candidate genes assessment

2014-15

Brian Key (UQ)

50

504

 1.020RI

Brain cells from blood

2014-15

Paul Dawson (MMRI)

40

174

 1.019RI

Transcription analyses of human brain tissue

2014-14

Irina Voineagu (UNSW)

50

333

1.033RI

Brain Connectivity in ASD

2015-

Linda Richards (QBI)

50

104

  1. http://minister.industry.gov.au/ministers/macfarlane/media-releases/31-million-investment-autism-research
  2. [SNP = Single Nucleotide Polymorphism; CNV = Copy Number Variant]
  3. CRC Living with Autism Annual Report

    http://www.autismcrc.com.au/sites/default/files/Autism%20CRC%20Annual%20Report%202014-15%20web.pdf
  4. Charles Claudianos is now at Monash University

The CRC's Annual Report for 2015/16 shows details of cash funding and In-Kind Value for Program 1 provided by the various institutions (mainly universities) involved5. The basic (genetic/biochemical) research projects listed are:

Project

Short title

Years

Lead Investigator/

Institution

Project Funds ($k)

In-Kind Value ($k)

1.002RC

Creation of biobank

2013-16

Andrew Whitehouse (UWA)

152

751

1.003RC

Genetic screening (Phase 1)

2013-16

Charles Claudianos (UQ)4

175

511

 1.019RI

Transcription analyses of human brain tissue. Post mortem brain6

2014-14

Irina Voineagu (UNSW)

50

333

 1.020RI

Brain cells from blood (BrainsTorm Study)6

2014-15

Paul Dawson (MMRI)

40

174

1.033RI

Brain Connectivity in ASD

2015-16

Linda Richards (QBI)

50

104

 1.042RC

System Genomics

2015-18

Jake Gratten (UQ)

1,743

3,009

 

5.https://www.autismcrc.com.au/sites/default/files/Autism%20CRC%20Annual%20Report%202015-16.pdf

6. Completed